Diagnosis of Tuberculosis: Molecular Technology

• Nucleic Acid Probes - from culture

  M.tb., M.tb. complex, M. avium, M. kansasii, M. gordonae
  

• PCR and other Amplification Methods (from clinical specimen)

  Smear positive specimens 93% sens and 98% spec
  
  Smear negative specimens < 70% sensitive

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