PPT Slide

Bacterial Cell

50

50

50

30

30

30

DHFA

THFA

Ribosomes

mRNA

DNA

CycloserineVancomycin, TeichoplaninBacitracinPenicillinsCephalosporinsMonobactamsCarbapenems

DNA gyrase

Cell wall synthesis

Quinolones

Folic acid metabolism

Trimethoprim

Sulfonamides

Periplasmic space

b-Lactamases

Aminoglycoside-modifyingenzymes

PABA

Cell membrane

Polymyxins

ChloramphenicolTransacetylase

Protein synthesis (t RNA)

StreptomycinGentamicin, Tobramycin (aminoglycosides)Amikacin

TetracyclineSpectinomycin

Protein synthesis (30 S Inhibitors)

Erythromycin (Macrolides)ChloramphenicolClindamycin

Protein synthesis (50 S Inhibitors)

Cell wall

Rifampin

DNA-directed RNA polymerase

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